Xeon E 2488 's Advantages
Released 2 years and 3 months late
Higher specification of memory (DDR5-4800 vs DDR4-3200)
Newer PCIe version (5 vs 4)
Higher base frequency (3.2GHz vs 2.8GHz)
Larger L3 cache size (24MB vs 16MB)
More modern manufacturing process (10nm vs 14nm)
Intel Xeon E 2378G 's Advantages
Lower TDP (80W vs 95W)