AMD EPYC 7643 's Advantages
Lower TDP (225W vs 320W)
AMD EPYC 9384X 's Advantages
Released 2 years and 3 months late
Higher specification of memory (DDR5-4800 vs DDR4-3200)
Newer PCIe version (5 vs 4)
Higher base frequency (3.1GHz vs 2.3GHz)
Larger L3 cache size (768MB vs 256MB)
More modern manufacturing process (5nm vs 7nm)