Opteron 6380 's Advantages
Lower TDP (115W vs 205W)
Intel Xeon Platinum 8280M 's Advantages
Released 6 years and 1 months late
Higher specification of memory (DDR4-2933 vs DDR3)
Newer PCIe version (3 vs 2)
Higher base frequency (2.7GHz vs 2.5GHz)
Larger L3 cache size (38.5MB vs 8MB)