Opteron 6272 's Advantages
Lower TDP (115W vs 160W)
AMD EPYC 8224P 's Advantages
Released 11 years and 10 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 2)
Higher base frequency (2.55GHz vs 2.1GHz)
Larger L3 cache size (64MB vs 16MB)
More modern manufacturing process (5nm vs 32nm)