Opteron 6180 SE 's Advantages
Higher base frequency (2.5GHz vs 2GHz)
Lower TDP (140W vs 170W)
AMD EPYC 7401P 's Advantages
Released 6 years and 4 months late
Higher specification of memory (DDR4-2666 vs DDR3-1333)
Newer PCIe version (3 vs 2)
Larger L3 cache size (64MB vs 12MB)
More modern manufacturing process (14nm vs 45nm)