Intel Xeon w5 2445 's Advantages
Released 10 years and 11 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (26.25MB vs 10MB)
More modern manufacturing process (10nm vs 32nm)
Intel Xeon E5 2643 's Advantages
Higher base frequency (3.3GHz vs 3.1GHz)
Lower TDP (130W vs 175W)