Intel Xeon W3680 's Advantages
Higher base frequency (3.333GHz vs 3.2GHz)
Xeon E 2488 's Advantages
Released 13 years and 9 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (24MB vs 12MB)
More modern manufacturing process (10nm vs 32nm)
Lower TDP (95W vs 130W)