Intel Xeon E3 1225 v2 's Advantages
Lower TDP (77W vs 80W)
Intel Xeon E3 1280 v5 's Advantages
Released 3 years and 5 months late
Higher specification of memory (DDR4 vs DDR3)
Higher base frequency (3.7GHz vs 3.2GHz)
More modern manufacturing process (14nm vs 22nm)