Intel Xeon E3 1220 's Advantages
Higher base frequency (3.1GHz vs 2.75GHz)
Lower TDP (80W vs 225W)
AMD EPYC 7453 's Advantages
Released 9 years and 11 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (4 vs 3)
Larger L3 cache size (64MB vs 8MB)