Opteron 6380 's Advantages
Lower TDP (115W vs 205W)
Intel Xeon Gold 6354 's Advantages
Released 8 years and 5 months late
Higher specification of memory (DDR4-3200 vs DDR3)
Newer PCIe version (4 vs 2)
Higher base frequency (3GHz vs 2.5GHz)
Larger L3 cache size (39MB vs 8MB)