Opteron 6366 HE 's Advantages
Lower TDP (85W vs 300W)
Intel Xeon Platinum 8461V 's Advantages
Released 10 years and 2 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 2)
Higher base frequency (2.2GHz vs 1.8GHz)
Larger L3 cache size (97.5MB vs 8MB)