Intel Xeon E5649 's Advantages
Higher base frequency (2.533GHz vs 2GHz)
Lower TDP (80W vs 270W)
Intel Xeon Platinum 8581V 's Advantages
Released 12 years and 10 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (300MB vs 12MB)
More modern manufacturing process (10nm vs 32nm)