Intel Xeon E5 2643 v3 's Advantages
Higher specification of memory (DDR4-2133 vs DDR4)
Higher base frequency (3.4GHz vs 2.7GHz)
Lower TDP (135W vs 205W)
Intel Xeon Platinum 8280 's Advantages
Released 4 years and 3 months late
Larger L3 cache size (38.5MB vs 20MB)
More modern manufacturing process (14nm vs 22nm)