Intel Xeon E3 1280 's Advantages
Higher base frequency (3.5GHz vs 2.5GHz)
Lower TDP (95W vs 205W)
Intel Xeon Platinum 8180M 's Advantages
Released 6 years and 3 months late
Higher specification of memory (DDR4 vs DDR3)
Larger L3 cache size (38.5MB vs 8MB)
More modern manufacturing process (14nm vs 32nm)