AMD EPYC 9454 's Advantages
Released 11 years and 9 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 2)
Higher base frequency (2.75GHz vs 2.533GHz)
Larger L3 cache size (256MB vs 12MB)
Intel Xeon E5649 's Advantages
Lower TDP (80W vs 290W)